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Three Part Question

In [patients with acute hepatic failure not caused by paracetamol] does [N-acetylcysteine] [improve morbidity or mortality]

Clinical Scenario

A pleasant elderly gentleman presents to the emergency department following a recent return from the Indian subcontinent. He is nauseated, feels tired and is clearly jaundiced. His blood tests confirm a hepatitis, and further tests confirm that this is secondary to a viral hepatitis infection. There is NO evidence of paracetamol overdose. A few hours later, you are called to see him as he has become increasingly confused. He is encephalopathic, and repeat bloods show he is developing a coagulopathy. You diagnose acute liver failure, and institute supportive measures. Your colleague states that you should start him on N-acetylcysteine (Parvolex), but you tell him not to be silly, as there is no paracetamol involved. However, he insists that N-acetylcysteine will still be beneficial. You wonder if there is any evidence behind his words.