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Methoxyflurane versus procedural sedation for anterior shoulder dislocation reduction

Three Part Question

In [adult patients with anterior shoulder dislocation] is [methoxyflurane a valid alternative to procedural sedation and analgesia] at [decreasing pain, Emergency Department length of stay (ED LOS) and facilitating successful reduction]

Clinical Scenario

A young man attends the emergency department having sustained an acute anterior shoulder dislocation in a rugby tackle. Peripheral venous access has not yet been obtained. You wonder if inhaled methoxyflurane (MF) could be as effective as procedural sedation and analgesia (PSA) in facilitating successful shoulder reduction whilst reducing length of departmental stay.

Search Strategy

Medline 1966-07/2022 using the OVID interface and Embase using the Embase database.
[methoxyflurane OR penthrox] AND [shoulder dislocation OR anterior shoulder dislocation OR glenohumeral dislocation]. LIMIT to human adults (>=16 years) and English language. The search strategy was last applied on 11 October 2022