Naloxone Titration vs Bolus doses in acute opioid overdose

Report By: Oliver Hobbs - Specialist Paramedic
Institution: Manchester Metropolitan University
Date Submitted: 29th October 2020
Last Modified: 29th October 2020
Status: Red (incomplete)

Three Part Question

[In adults presenting with acute opioid overdose in the prehospital setting] does [titration of Naloxone in quantities to reverse respiratory and cardiovascular depression whilst maintained reduced GCS as opposed to regular bolus doses] [reduce acute withdrawal and mortality]