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Intranasal Lorazepam Is an Acceptable Alternative To Intravenous Lorazepam In The Control Of Acute Seizures In Children

Three Part Question

In [children presenting to the ED with seizures] is [intranasal Lorazepam an acceptable intervention] for achieving [termination of seizures]?

Clinical Scenario

A 4 year old child is brought to the Emergency Department by her parents. She presents with protracted seizures. It proves difficult to gain intravenous access for administration of IV Lorazepam, which is the standard of care. You wonder whether intranasal administration of Lorazepam may be an acceptable alternative.

Search Strategy

PubMed using MeSH database
Search terms “Seizures” [Mesh] AND “Lorazepam” [Mesh] AND (intranasal OR intravenous)

Search Outcome