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Outpatient treatment of PE in pregnancy.

Three Part Question

In [pregnant women with a suspected PE] presenting to the ED is [outpatient treatment] for PE [safe]?

Clinical Scenario

A 25-year old pregnant woman presents to the ED with acute onset pleuritic chest pain, which you confidently diagnose as a PE. You start her on LMWH and consider whether you can discharge her and treat her on an outpatient basis safely.

Search Strategy

All EBM Reviews - Cochrane DSR, ACP Journal Club, DARE, CCTR, CMR, HTA, and NHSEED 2nd Quarter 2008. EMBASE 1996 to 2008 week 25. Medline 1950-Week 2 June 2008 using the OVID interface. CINAHL 1982 to June Week 2 2008
([{pregnanc$.mp. OR exp Pregnancy OR exp Pregnancy Complications or OR exp Pregnant Women}] AND [exp Pulmonary Embolism OR pulmonary embolu$.mp. OR pulmonary OR exp Venous Thrombosis/ pleuri$.mp. OR pulmonary embol$.mp.]) AND {exp Ambulatory Care OR outpatient treatment$.mp. OR exp Outpatient Clinics, Hospital OR treatment$.mp. OR exp Therapeutics} AND {safety$.mp. or exp Safety}
LIMIT to human AND english.

Search Outcome

1350 papers were found of which 0 were relevant.


There is no direct evidence that can assist in answering this question.

Clinical Bottom Line

Local advice preferably from obstetricians as well as ED consultants should be followed.