A 30-year-old patient presents to the emergency department with knee pain for 48 hours, fever, and decreased range of motion at the knee. She has a history of type II diabetes and no prior orthopedic surgeries. Reports left knee swelling, redness, feels warm to the touch, and denies traumatic injury. The patient is unable to bear weight on the extremity and range of motion is painful. Arthrocentesis demonstrates findings consistent with septic arthritis. You wonder if oral antibiotics are are as effective intravenous (IV) antibiotics for treatment.
32 year old female fit and healthy, presented with excessive hair loss for the past 1 year. She was investigated thoroughly and diagnosed with Androgenic Alopecia. She tried topical minoxidil and other oral supplements and found some improvements. She heard about PRP and wanted to have the treatment.
Corticosteroids in patients with community-acquired pneumonia
A 62-year-old man presents to the ED with fever, productive cough, tachypnea, and hypoxia. His chest X-ray shows right lower lobe consolidation, and his CURB-65 score is 3, indicating severe community-acquired pneumonia. Despite appropriate antibiotics and fluids, he remains hypotensive and requires escalating oxygen support. The ED team wonders whether adding systemic corticosteroids could improve outcomes or reduce the likelihood of ICU admission.
An adult patient presents to the emergency department with a painful hip fracture requiring analgesia before definitive management. You consider performing an ultrasound-guided regional nerve block and wonder whether the pericapsular nerve group (PENG) block provides superior analgesia compared with the fascia iliaca compartment block (FICB).
Is Doppler ultrasound superior to nuclear scintigraphy for diagnosing testicular torsion?
An 18-year-old man presents to the emergency department with a 4-hour history of sudden-onset severe left testicular pain associated with nausea and vomiting. On examination, the left testis is high-riding, swollen, and extremely tender, with an absent cremasteric reflex. You call the urology registrar, who is concerned about testicular torsion. The emergency department has immediate access to colour Doppler ultrasound, while nuclear scintigraphy is also available through the radiology department. You wonder whether Doppler ultrasound is superior to nuclear scintigraphy for diagnosing testicular torsion.
Oscillometric versus femoral intra-arterial blood pressure in prehospital critical care
A 25-year-old man has been struck by a car. He has sustained a severe head injury and significant blunt chest trauma. He is unconscious, tachycardic and peripherally cold, with repeated oscillometric blood-pressure measurements that are low, variable and occasionally unobtainable. The prehospital critical-care team needs reliable blood-pressure measurements to balance treatment of suspected haemorrhagic shock against the need to maintain adequate cerebral perfusion. They consider inserting a femoral arterial line and wonder how accurately oscillometric non-invasive blood-pressure monitoring reflects femoral intra-arterial pressure in this setting.
An unknown 24-year-old patient is brought to the emergency department (ED) by ambulance after having been found unresponsive in a hotel room. They are hypotensive, unresponsive, and breathing very slowly. The paramedics inform you that empty medication packets were found on the scene, including diazepam. As you prepare equipment for emergency intubation, one of your team suggests a trial of flumazenil. You are worried that it could cause a seizure – but is there is evidence for this?
A patient presents to the Emergency Department with acute upper gastrointestinal bleeding and is awaiting endoscopy. Intravenous proton pump inhibitor therapy is commenced before endoscopic evaluation. The treating team questions whether administration of PPI therapy before endoscopy improves patient outcomes compared with no pre-endoscopic PPI therapy
A patient presents to the emergency department with a simple leg laceration requiring sutured closure. Traditional teaching often emphasizes precise approximation and wound edge eversion to optimize healing and cosmetic outcome. However, increasing attention has been directed toward wound tension as a potentially more important determinant of scar formation and wound integrity. You wonder whether low-tension closure techniques improve healing outcomes compared with standard interrupted closure methods.
Management of Lateral Ankle Sprains: Semi-rigid Brace or Soft Ace Bandage
A 23-year-old patient presents to the Emergency Department with the chief complaint of ankle pain after inversion injury while playing soccer. The patient has tenderness, edema, and ecchymosis over the lateral aspect of the ankle, with positive anterior drawer and talar tilt tests. X-rays are negative for fracture. As the treating physician, you diagnose the patient with a lateral ankle sprain and prepare their discharge recommendations. You wonder if placing them in a semi-rigid brace versus using an ACE wrap will help the young athlete return to play sooner.
A 58-year-old male suffers a witnessed collapse at home and receives immediate bystander cardiopulmonary resuscitation (CPR). Paramedics arrive 7 minutes after arrest onset; he is found to be in pulseless electrical activity (PEA) at the initial rhythm check and is given epinephrine 1 mg intravenous (IV). He is transported to the emergency department (ED) where resuscitation is continued and on subsequent rhythm checks he remains in PEA. As you consider additional treatments, you wonder what the optimal time interval is for additional doses of epinephrine.
You are working overnight as a registrar in a Major Trauma Centre. A patient is builder is brought in with a significant crush injuries to his legs after being run over by a digger. Due to environmental challenges he remained trapped beneath the digger for a prolonged period whilst the Emergency Services freed him. Following hand over, the critical care paramedic advises that the team had had a discussion at the scene as to whether to apply a tourniquet or not and she asks if you know of any evidence for or against its use in the management of patients with crush injuries to the limbs.
What is the optimum fluid resuscitation strategy in suspected crush injury?
A 28 year old lorry driver comes in to ED following an RTC. His legs were trapped and crushed and due to the location of the incident, it took a very long time for the fire service to extricate him. When he presents to ED, you ask yourself - I know this man is at risk of rhabdomyolysis and needs intravenous fluids to manage this but - what is the best fluid resuscitation strategy?
A patient with recurrent melasma seeks alternatives to hydroquinon. The clinician considers TXA delivered via micro needling and wants to evaluate the efficacy.
You are working in a busy emergency department when a 34-year-old woman presents with a severe acute migraine. She has a well-established diagnosis of episodic migraine and has already taken a triptan and NSAID without relief. She is photophobic and vomiting, and is reluctant to receive intravenous medications because of a previous adverse reaction to metoclopramide. You wonder whether a greater occipital nerve block could improve her acute pain relief.
What is the optimum strategy to manage potential hyperkalaemia associated with crush injury?
A 23 year old farmer presents to the Emergency Department having trapped his legs by a piece of falling machinery. He is diagnosed with a crush injury of the lower limbs. Initial blood gas results show a potassium of 7mmol/L. You want to provide the optimum strategy for managing the hyperkalaemia.
A 25-year-old male has sustained a gunshot wound to the thorax in a hunting accident. On-scene, emergency medical services find that he is sitting upright, appears anxious, has jugular venous distention, and has weak peripheral pulses. Bleeding is grossly controlled. Vital signs include a heart rate of 128 bpm, blood pressure of 92/68 mmHg, respiratory rate of 26/min, oxygen saturation of 95% on 4L/min by nasal cannula, and temperature of 36.2 °C. Emergency medical services must decide between taking the patient directly to a level 1 trauma center forty-five minutes away, or to the critical access emergency department five minutes away.
A 30-year-old emergency medicine resident is working an evening shift on a July weekend at a busy Level 1 Trauma Center. She’s already five charts behind, and more patients are filing into the waiting room by the second. As she heads in to see her next patient, she thinks about all the documentation that awaits her once her shift is over. She wonders if using the latest AI-assisted charting tool her residency program just rolled out will help her complete her documentation and get her home on time.
A 16 year old girl is brought into the Emergency Department after falling from a horse, which subsequently rolled on top of her and she has sustained crush injuries to both her legs. You are aware that the sequalae of crush injuries include hyperkalaemia and metabolic acidosis - logically you question whether the administration of intravenous sodium bicarbonate may be of benefit to this patient and want to know if there is any evidence to support its use.
Does early renal replacement therapy reduce morbidity or mortality in patients with crush injury?
You are the ICU registrar working in a over night in a Major Trauma Centre. A 32 year old man, who had been caving with friends, has been brought in to the Emergency Department, after sustaining a crush injury to both his legs when a large boulder in the cave system they were exploring dislodged and trapped him. Due to the remote location of the incident and challenges of the environment he remained trapped for a prolonged period before being extricated and brought to hospital. You are aware that crush syndrome can cause Acute Renal Failure and wonder whether if commencing Renal Replacement Therapy early on in this patient's care would be beneficial.
